SCHEMBL186093

SCHEMBL186093

Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(/N=N/c3ccccc3)c(O)c12.[NaH].[NaH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 2/20 0.68
CYP1A2 P05177 2/20 0.64
MEN1 O00255 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 1/20 0.64
ENPP2 Q13822 8/20 0.62
SUMO2 P61956 1/20 0.55
SUMO1 P63165 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP2 Q9HC62 1/20 0.55
CYP2C9 P11712 1/20 0.54
MAPK1 P28482 1/20 0.54
DNASE1L3 Q13609 1/20 0.54
PRMT1 Q99873 2/20 0.54
PRMT3 O60678 1/20 0.48
EP300 Q09472 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
NT5E P21589 1/20 0.47
POLB P06746 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19513949 1.00 PHLPP2 (0.68) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL27752533 1.00 PHLPP2 (0.68) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL344209 0.99 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL29377534 0.99 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL186095 0.99 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL113323 0.99 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL7065494 0.92 PHLPP2 (0.72) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL16675030 0.91 PHLPP2 (0.61) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL19513948 0.90 PHLPP2 (0.62) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL14493380 0.89 PHLPP2 (0.63) PHLPP2CYP1A2MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP claimed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 US disclosed
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2014-10-09 US disclosed
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2014-10-02 US disclosed
US-8551190-B2 Process for producing a colorant for keratin fibers HENKEL AG & CO. KGAA (DE) 2013-10-08 US disclosed
US-8545576-B2 Process for producing a colorant for keratin fibers HENKEL AG & CO., KGAA (DE) 2013-10-01 US disclosed
US-8545575-B2 Process for producing a colorant for keratin fibers HENKEL AG & CO. KGAA (DE) 2013-10-01 US disclosed
US-20130174356-A1 PROCESS FOR PRODUCING A COLORANT FOR KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2013-07-11 US disclosed
US-20130174354-A1 PROCESS FOR PRODUCING A COLORANT FOR KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2013-07-11 US disclosed
US-20070000069-A1 Agent for colouring keratin fibres HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2007-01-04 US disclosed
EP-1733760-A1 Colourants for keratin fibres comprising certain cationic cellulose ether derivatives Wella Aktiengesellschaft (DE) 2006-12-20 EP disclosed
US-20050112074-A1 Hair treatment composition comprising composite particles of clay and charged organic molecule UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-05-26 US disclosed
EP-1455740-A1 HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE Unilever Plc (GB) 2004-09-15 EP disclosed
US-20030163877-A1 Colouring composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-09-04 US disclosed
WO-2003047541-A1 HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE UNILEVER PLC (GB) 2003-06-12 WO disclosed
EP-1317917-A1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2003-06-11 EP disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 US disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-6146429-A DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS WELLA AKTIENGESELLSCHAFT (DE) 2000-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES KRT18, DSG1, PKN1 PHLPP2 2012/4885CYP1A2 1749/4885MEN1 4097/4885
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, PKN3, IK PHLPP2 4448/4885CYP1A2 3680/4885MEN1 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.