Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610120 | 0.87 | HDAC1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL14419498 | 0.83 | MAPT (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL18615438 | 0.82 | KMT2A (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL18609813 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL31293950 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28212176 | 0.78 | HTT (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL2011023 | 0.78 | MEN1 (1.00) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL10604241 | 0.77 | MEN1 (0.80) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL2386068 | 0.76 | KMT2A (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4317042 | 0.76 | KMT2A (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038871-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |