Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.33 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18584441 | 0.92 | PPARG (0.37) | PPARGHSD17B1ADORA3MAOBADORA2A | |
| SCHEMBL18609946 | 0.92 | PPARG (0.37) | PPARGHSD17B1ADORA3MAOBADORA2A | |
| SCHEMBL16548252 | 0.88 | PPARG (0.40) | PPARGPPARDPPARAHSD17B1FFAR4 | |
| Hydrochloric Acid SCHEMBL17939982 | 0.87 | PPARG (0.40) | PPARGPPARDPPARAHSD17B1FFAR4 | |
| SCHEMBL18610031 | 0.85 | CASR (0.38) | ADORA3MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL17945892 | 0.82 | CASR (0.41) | FFAR4FFAR1 | |
| Hydrochloric Acid SCHEMBL17939802 | 0.81 | CASR (0.41) | FFAR4FFAR1 | |
| SCHEMBL18609947 | 0.80 | HSD17B1 (0.35) | HSD17B1ADORA3MAOBADORA2AADORA2B | |
| SCHEMBL18609603 | 0.80 | MEN1 (0.38) | ADORA3MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL17939844 | 0.79 | PPARG (0.37) | PPARGHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |