Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859251 | 0.83 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL1859249 | 0.83 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL1868136 | 0.82 | CYP19A1 (0.52) | CYP19A1 | |
| SCHEMBL1867163 | 0.79 | CYP19A1 (0.46) | CYP19A1P4HB | |
| SCHEMBL1865610 | 0.77 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL1868143 | 0.77 | CYP19A1 (0.49) | CYP19A1P4HB | |
| SCHEMBL1857255 | 0.76 | CYP19A1 (0.46) | CYP19A1P4HB | |
| SCHEMBL1856343 | 0.75 | CYP19A1 (0.43) | CYP19A1P4HB | |
| SCHEMBL1859929 | 0.75 | SHBG (0.43) | CYP19A1 | |
| SCHEMBL1656805 | 0.73 | AR (0.58) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | claimed |
| US-7939517-B2 | 1,4,6-androstatriene-3,17-dione (“ATD”) for therapeutic uses | KNELLER BRUCE W | 2011-05-10 | — | — | US | disclosed |
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | disclosed |