Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.50 |
| ▸ | ACP1 | P24666 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610024 | 0.89 | CASR (0.42) | CASRACP1 | |
| SCHEMBL18610312 | 0.86 | CASR (0.56) | CASRMAPK1 | |
| SCHEMBL17939923 | 0.83 | CASR (0.59) | CASRACP1SMN1; SMN2MEN1LMNA | |
| SCHEMBL17939892 | 0.83 | CASR (0.59) | CASRACP1SMN1; SMN2MEN1LMNA | |
| SCHEMBL16548161 | 0.83 | CASR (0.59) | CASRACP1SMN1; SMN2MEN1LMNA | |
| SCHEMBL18610028 | 0.83 | CASR (0.58) | CASRACP1MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL16540022 | 0.82 | CASR (0.58) | CASRACP1SMN1; SMN2MEN1LMNA | |
| SCHEMBL18610316 | 0.81 | CYP11B1 (0.40) | CASRROCK2ROCK1PRKG1CYP3A4 | |
| SCHEMBL18609855 | 0.79 | PFKFB3 (0.40) | CASRROCK2ROCK1PRKG1CYP3A4 | |
| SCHEMBL18609940 | 0.79 | PLK1 (0.38) | CASRROCK2ROCK1PRKG1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |