Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610027 | 0.89 | CASR (0.45) | CASRMEN1KMT2AACP1 | |
| SCHEMBL18610313 | 0.87 | CASR (0.43) | CASR | |
| SCHEMBL18610025 | 0.83 | CASR (0.50) | CASRMEN1KMT2AACP1POLB | |
| SCHEMBL18610135 | 0.77 | ATM (0.41) | CASRACP1POLB | |
| SCHEMBL17945772 | 0.76 | CASR (0.71) | CASR | |
| SCHEMBL18609838 | 0.76 | ALDH1A1 (0.40) | CASRACP1POLB | |
| SCHEMBL18610024 | 0.76 | CASR (0.42) | CASRACP1 | |
| SCHEMBL18609844 | 0.75 | CASR (0.39) | CASRACP1POLB | |
| SCHEMBL23587995 | 0.75 | CASR (0.52) | CASRMEN1KMT2AACP1POLB | |
| SCHEMBL18609950 | 0.73 | CASR (0.50) | CASRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |