Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 16/20 | 0.62 |
| ▸ | CHIA | Q9BZP6 | 11/20 | 0.62 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.40 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18607793 | 1.00 | CHIT1 (0.62) | CHIT1CHIACHI3L1CHI3L2KCNH2 | |
| SCHEMBL18589493 | 1.00 | CHIT1 (0.62) | CHIT1CHIACHI3L1CHI3L2KCNH2 | |
| SCHEMBL18608069 | 1.00 | CHIT1 (0.62) | CHIT1CHIACHI3L1CHI3L2KCNH2 | |
| Hydrochloric Acid SCHEMBL18577310 | 0.99 | CHIT1 (0.61) | CHIT1CHIACHI3L1CHI3L2KCNH2 | |
| SCHEMBL18607936 | 0.91 | CHIT1 (0.64) | CHIT1CHIACHI3L1KCNH2 | |
| SCHEMBL18577362 | 0.91 | CHIT1 (0.64) | CHIT1CHIACHI3L1KCNH2 | |
| SCHEMBL18587194 | 0.83 | CHIT1 (0.62) | CHIT1CHIACHI3L1CHI3L2KCNH2 | |
| SCHEMBL18586427 | 0.83 | CHIA (0.64) | CHIT1CHIAKCNH2 | |
| SCHEMBL18586428 | 0.83 | CHIA (0.64) | CHIT1CHIAKCNH2 | |
| Hydrochloric Acid SCHEMBL18577385 | 0.82 | CHIA (0.63) | CHIT1CHIAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |
| WO-2017037670-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2017-03-09 | — | — | WO | disclosed |