⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313155 | 0.75 | ADH1A (0.33) | — | |
| SCHEMBL16624 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL29125369 | 0.69 | — | — | |
| SCHEMBL112606 | 0.68 | — | — | |
| SCHEMBL2127334 | 0.67 | — | — | |
| SCHEMBL1247281 | 0.65 | — | — | |
| SCHEMBL15566971 | 0.64 | — | — | |
| SCHEMBL12422793 | 0.63 | — | — | |
| SCHEMBL16612023 | 0.63 | — | — | |
| SCHEMBL9157320 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368356-A | Bicyclic heterocyclic compounds and their therapeutic use | 阿斯特克斯治疗有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109336883-B | Bicyclic heterocyclic compounds and their therapeutic use | 阿斯特克斯治疗有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-108026095-B | Novel compounds | 詹森药业有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-108137546-B | Bis-heteroaryl substituted 1, 4-benzodiazepine compounds and their use for the treatment of cancer | 詹森药业有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-111902415-A | Pharmaceutical compounds | 大冢制药株式会社 | 2020-11-06 | — | — | CN | disclosed |
| CN-106459010-B | Quinoxaline derivatives as FGFR kinase modulators | 阿斯特克斯治疗有限公司 | 2020-11-03 | — | — | CN | disclosed |
| EP-2442831-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | The University Of Bath (GB) | 2012-04-25 | — | — | EP | disclosed |
| US-7947703-B2 | Phenanthridinium derivatives as DNA binding agents | UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2011-05-24 | — | — | US | disclosed |
| WO-2010146362-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | THE UNIVERSITY OF BATH (GB) | 2010-12-23 | — | — | WO | disclosed |
| WO-2005016919-A1 | AMINOPYRONES AND THEIR USE AS ATM INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005002673-A1 | RAF KINASE INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |
| WO-2004080976-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2004-09-23 | — | — | WO | disclosed |
| EP-1417196-A1 | DNA-PK INHIBITORS | Cancer Research Technology Limited (GB) | 2004-05-12 | — | — | EP | disclosed |
| EP-1397350-A1 | ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2004004720-A1 | 3-`(HETERO) ARYLMETHOXY ! PYRIDINES AND THEIR ANALOGUES AS P38 MAP KINASE INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-01-15 | — | — | WO | disclosed |
| EP-1330442-A1 | PHTHALAZINONE DERIVATIVES | Kudos Pharmaceuticals Limited (GB) | 2003-07-30 | — | — | EP | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| WO-2002090334-A1 | ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002036576-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2002-05-10 | — | — | WO | disclosed |