SCHEMBL18613014

SCHEMBL18613014

c1ccc2c(c1)Nc1cnccc1O2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.65
MAPT P10636 3/20 0.44
GAA P10253 2/20 0.44
IDO1 P14902 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
DHODH Q02127 1/20 0.42
HTR2B P41595 2/20 0.37
HTR7 P34969 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ACHE P22303 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
IKBKB O14920 1/20 0.36
AURKA O14965 1/20 0.36
CHUK O15111 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PIM1 P11309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxazine SCHEMBL7862 0.81 ALOX5 (1.00) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL28844098 0.81 ALOX5 (1.00) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL6310178 0.81 ALOX5 (1.00) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL29355714 0.81 ALOX5 (1.00) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL29224707 0.80 ALOX5 (0.71) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL27881118 0.80 ALOX5 (0.71) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL25275195 0.79 ALOX5 (0.94) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL29212121 0.79 ALOX5 (0.94) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL31267446 0.79 ALOX5 (0.94) ALOX5MAPTGAAL3MBTL1NPSR1
Phenoxazine SCHEMBL20840431 0.79 ALOX5 (0.94) ALOX5MAPTGAAL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381578-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-13 US disclosed
WO-2017040965-A1 LUBRICANT COMPOSITION BASF SE (DE) 2017-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381578-B2 Organometallic compound and organic light-emitting device including the same L1CAM, MSL1, CHRM1 ALOX5 2218/4885MAPT 1595/4885GAA 3967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.