Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209194 | 1.00 | DHODH (0.66) | DHODHL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5969916 | 0.87 | EPHX2 (0.51) | DHODHL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL29551628 | 0.85 | HTT (0.59) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5714269 | 0.85 | HTT (0.59) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL18761357 | 0.85 | HTT (0.59) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24804264 | 0.83 | EPHX2 (0.60) | DHODHL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL2463602 | 0.82 | TAOK1 (0.55) | ALDH1A1 | |
| SCHEMBL26999632 | 0.80 | EPHX1 (0.57) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2406505 | 0.79 | ALDH1A1 (0.76) | DHODHL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1565743 | 0.79 | ALDH1A1 (0.76) | DHODHL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037022-A1 | COMPOUNDS AND METHODS USEFUL FOR TREATING OR PREVENTING HEMATOLOGICAL CANCERS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-03-09 | — | — | WO | disclosed |