Sugi Predict

Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL18614907

CC(C)[C@H](N)C(=O)O.N[C@@H](CO)C(=O)OC(=O)[C@@H](N)Cc1c[nH]cn1.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.44
▸ TPH1 P17752 3/20 0.36
▸ PCNA P12004 1/20 0.34
▸ PTGS1 P23219 2/20 0.33
▸ ITGB3 P05106 1/20 0.33
▸ ITGA2B P08514 1/20 0.33
▸ ALPI P09923 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ XIAP P98170 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ FYN P06241 1/20 0.33
▸ ADORA3 P0DMS8 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ PTGS2 P35354 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL18614906 0.92 SLC7A5 (0.50) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL18614909 0.92 SLC7A5 (0.50) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL16540226 0.89 SLC7A5 (0.39) SLC7A5TPH1PCNAITGB3ITGA2B
Tyrosine SCHEMBL16540106 0.87 SLC7A5 (0.38) SLC7A5TPH1PTGS1ALPIPKM
Tyrosine SCHEMBL28519346 0.84 SLC7A5 (0.55) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL606712 0.83 SLC7A5 (0.65) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL28433898 0.83 SLC7A5 (0.65) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL8315968 0.83 SLC7A5 (0.65) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL606713 0.83 SLC7A5 (0.65) SLC7A5TPH1PCNAPTGS1ITGB3
Tyrosine SCHEMBL8316690 0.83 SLC7A5 (0.65) SLC7A5TPH1PCNAPTGS1ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294827-A1 PARAOXONASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS Theripion, Inc. (US) 2023-12-27 — — EP disclosed
WO-2018136163-A2 TANDEM APOA-1 FUSION POLYPEPTIDES THERIPION, INC. (US) 2018-07-26 — — WO disclosed
EP-3328881-A1 APOA-1 FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS Theripion, Inc. (US) 2018-06-06 — — EP disclosed
WO-2017044424-A1 APOA-1 FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS THERIPION, INC. (US) 2017-03-16 — — WO disclosed