Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20357199 | 0.99 | PARP10 (0.58) | PARP10PARP15PARP2NR1H4OPRK1 | |
| SCHEMBL201939 | 0.94 | PARP10 (0.67) | PARP10PARP15PARP2NR1H4OPRK1 | |
| SCHEMBL7439527 | 0.87 | PARP10 (0.69) | PARP10PARP15PARP2NR1H4OPRK1 | |
| SCHEMBL20357322 | 0.83 | NR1H4 (0.55) | PARP10PARP15PARP2NR1H4OPRK1 | |
| SCHEMBL2639568 | 0.82 | NR1H4 (0.59) | PARP10PARP15PARP2NR1H4OPRK1 | |
| SCHEMBL30281276 | 0.81 | NR1H4 (0.76) | PARP10PARP15PARP2NR1H4 | |
| SCHEMBL3060401 | 0.81 | NR1H4 (0.76) | PARP10PARP15PARP2NR1H4 | |
| SCHEMBL13749857 | 0.80 | NR1H4 (0.56) | PARP10PARP15PARP2NR1H4LRRK2 | |
| SCHEMBL2087923 | 0.80 | NR1H4 (0.62) | PARP10PARP15PARP2NR1H4 | |
| SCHEMBL19405726 | 0.80 | PARP10 (0.71) | PARP10PARP15PARP2LRRK2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038873-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | PARP10 3800/4885PARP15 3998/4885PARP2 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.