SCHEMBL201939

SCHEMBL201939

NC(=O)c1cccc(OCC2CC2)c1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 7/20 0.67
PARP15 Q460N3 6/20 0.67
PARP2 Q9UGN5 3/20 0.67
NR1H4 Q96RI1 3/20 0.59
OPRK1 P41145 5/20 0.56
KCNH2 Q12809 2/20 0.54
PARP1 P09874 1/20 0.54
LRRK2 Q5S007 1/20 0.53
TNKS O95271 1/20 0.51
PARP14 Q460N5 1/20 0.51
TNKS2 Q9H2K2 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.51
ADORA2B P29275 1/20 0.48
ADORA1 P30542 1/20 0.48
OPRM1 P35372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18615435 0.94 PARP10 (0.60) PARP10PARP15PARP2NR1H4OPRK1
Hydrochloric Acid SCHEMBL20357199 0.93 PARP10 (0.58) PARP10PARP15PARP2NR1H4OPRK1
SCHEMBL7439527 0.93 PARP10 (0.69) PARP10PARP15PARP2NR1H4OPRK1
SCHEMBL20357322 0.88 NR1H4 (0.55) PARP10PARP15PARP2NR1H4OPRK1
SCHEMBL2639568 0.88 NR1H4 (0.59) PARP10PARP15PARP2NR1H4OPRK1
SCHEMBL3060401 0.86 NR1H4 (0.76) PARP10PARP15PARP2NR1H4
SCHEMBL30281276 0.86 NR1H4 (0.76) PARP10PARP15PARP2NR1H4
SCHEMBL13749857 0.85 NR1H4 (0.56) PARP10PARP15PARP2NR1H4LRRK2
SCHEMBL2087923 0.84 NR1H4 (0.62) PARP10PARP15PARP2NR1H4
SCHEMBL19405726 0.84 PARP10 (0.71) PARP10PARP15PARP2LRRK2TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108349901-B Phenyl derivatives as cannabinoid receptor 2 agonists 豪夫迈·罗氏有限公司 2022-08-16 CN claimed
CN-102008459-B Antibacterial agents BIOTA SCIENT MAN 2013-05-29 CN claimed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
EP-4143195-A1 IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 Janssen Pharmaceutica NV (BE) 2023-03-08 EP disclosed
CN-108349901-B Phenyl derivatives as cannabinoid receptor 2 agonists 豪夫迈·罗氏有限公司 2022-08-16 CN disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
CN-101404989-B Antibacterial agent PROLYSIS LTD 2011-10-05 CN disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
CN-102008459-A Antibacterial agents PROLYSIS LTD 2011-04-13 CN disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
CN-101404989-A Antibacterial agent PROLYSIS LTD (GB) 2009-04-08 CN disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 PARP10 2725/4885PARP15 4000/4885PARP2 758/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 PARP10 3006/4885PARP15 4164/4885PARP2 1356/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 PARP10 3006/4885PARP15 4164/4885PARP2 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.