Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615491 | 0.83 | KMT2A (0.48) | MEN1KMT2AKDM4EPOLBNPC1 | |
| SCHEMBL12218290 | 0.81 | KMT2A (1.00) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20357274 | 0.81 | KMT2A (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18615445 | 0.81 | KMT2A (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2752803 | 0.81 | KMT2A (0.73) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18615451 | 0.81 | MEN1 (0.69) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18615480 | 0.79 | MEN1 (0.66) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20357399 | 0.79 | KMT2A (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18615497 | 0.79 | KMT2A (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20365400 | 0.78 | KMT2A (0.72) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038873-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |