Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615621 | 0.87 | CYP1A2 (0.63) | MEN1KMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL18615685 | 0.84 | EPHX2 (0.62) | MEN1KMT2AEPHX2ALDH1A1MAPT | |
| SCHEMBL18615480 | 0.84 | MEN1 (0.66) | MEN1KMT2AEPHX2ALDH1A1MAPT | |
| SCHEMBL18615468 | 0.83 | EPHX2 (0.53) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL18615455 | 0.83 | EPHX2 (0.53) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL31440788 | 0.83 | KMT2A (0.61) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18615471 | 0.83 | EPHX2 (0.51) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL20365330 | 0.83 | KMT2A (0.67) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL18615457 | 0.83 | EPHX2 (0.63) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL18615787 | 0.82 | EPHX2 (0.52) | MEN1KMT2AEPHX2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017038873-A1 | UREA DERIVATIVE AND USE THEREFOR | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |