Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 8/20 | 0.35 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 5/20 | 0.33 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335451 | 0.93 | CTSL (0.38) | CTSLCTSKCTSSCTSBTACR2 | |
| SCHEMBL18617379 | 0.86 | NPC1 (0.42) | CTSLCTSKCTSSCTSBTACR2 | |
| SCHEMBL20341759 | 0.85 | CTSL (0.36) | CTSLCTSKCTSSCTSBTACR2 | |
| SCHEMBL18615858 | 0.84 | CTSL (0.37) | CTSLCTSKCTSS | |
| SCHEMBL18616005 | 0.84 | CTSL (0.37) | CTSLCTSKCTSS | |
| SCHEMBL23810273 | 0.84 | CTSL (0.36) | CTSLCTSKCTSSCTSBTACR2 | |
| SCHEMBL18616686 | 0.83 | CTSL (0.38) | CTSLCTSKCTSSCTSB | |
| SCHEMBL20341783 | 0.83 | CTSL (0.35) | CTSLCTSKCTSSTACR2 | |
| SCHEMBL18615860 | 0.83 | CTSL (0.35) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18616557 | 0.83 | CTSL (0.38) | CTSLCTSKCTSSCTSBTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-107922315-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |