Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174189 | 0.85 | CNR1 (0.42) | CNR1CSNK1DPTGER4LMNACA2 | |
| SCHEMBL12517203 | 0.82 | CYP1A2 (0.39) | CSNK1DLMNACA2CA4CCNE2 | |
| SCHEMBL10174188 | 0.80 | LMNA (0.44) | CNR1PTGER4LMNACCNE2CCNE1 | |
| SCHEMBL20350149 | 0.77 | CSNK1D (0.41) | CNR1CSNK1DLMNACA2CA4 | |
| SCHEMBL12024794 | 0.75 | PLAT (0.40) | CNR1LMNACA2CHIA | |
| SCHEMBL5045651 | 0.74 | CSNK2A1 (0.48) | SMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL13926052 | 0.74 | ATM (0.49) | LMNACA2GAAALDH1A1 | |
| SCHEMBL13753913 | 0.72 | CSNK2A1 (0.56) | LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL12024791 | 0.72 | HCRTR1 (0.55) | — | |
| SCHEMBL12024793 | 0.72 | CHIA (0.47) | LMNACHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037116-A1 | PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-09 | — | — | WO | disclosed |