Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617373 | 0.90 | MPO (0.53) | MPOKLKB1 | |
| SCHEMBL18585746 | 0.90 | MPO (0.53) | MPOKLKB1 | |
| SCHEMBL18616570 | 0.89 | MPO (0.53) | MPOKLKB1 | |
| SCHEMBL18586149 | 0.89 | MPO (0.66) | MPOKLKB1 | |
| SCHEMBL18617776 | 0.88 | MPO (0.50) | MPOKLKB1 | |
| SCHEMBL18585653 | 0.88 | MPO (0.50) | MPOKLKB1 | |
| SCHEMBL18617315 | 0.88 | MPO (0.50) | MPOKLKB1 | |
| SCHEMBL18585841 | 0.88 | MPO (0.73) | MPOKLKB1 | |
| SCHEMBL18617587 | 0.87 | MPO (0.58) | MPOKLKB1 | |
| SCHEMBL20658785 | 0.86 | MPO (0.48) | MPOKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |