Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341778 | 0.93 | CTSL (0.37) | CTSLCTSSCTSKCTSB | |
| SCHEMBL23810284 | 0.91 | CTSL (0.36) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18616632 | 0.91 | CTSL (0.36) | CTSLCTSSCTSKCTSB | |
| SCHEMBL23810253 | 0.91 | CTSL (0.35) | CTSLCTSSCTSKCTSB | |
| SCHEMBL23810311 | 0.89 | CTSL (0.34) | CTSLCTSSCTSK | |
| SCHEMBL18615979 | 0.86 | CTSL (0.32) | CTSL | |
| SCHEMBL20341764 | 0.83 | CTSL (0.38) | CTSLCTSSCTSKCTSB | |
| SCHEMBL20341771 | 0.83 | CTSL (0.38) | CTSLCTSSCTSKCTSB | |
| SCHEMBL20335438 | 0.83 | CTSL (0.38) | CTSLCTSSCTSKCTSB | |
| SCHEMBL20341786 | 0.83 | CTSL (0.38) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |