Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 7/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209534 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KCNK3ELANEPREPTAAR1 | |
| SCHEMBL20485170 | 0.90 | MEN1 (0.47) | ELANEPREPTAAR1MEN1KMT2A | |
| SCHEMBL18620640 | 0.90 | MEN1 (0.47) | ELANEPREPTAAR1MEN1KMT2A | |
| SCHEMBL22209415 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KCNK3ELANEPREPTAAR1 | |
| SCHEMBL18620590 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KCNK3ELANEPREPTAAR1 | |
| SCHEMBL22209498 | 0.84 | PREP (0.52) | ALDH1A1ELANEPREPTAAR1 | |
| SCHEMBL18621640 | 0.84 | PREP (0.52) | ALDH1A1ELANEPREPTAAR1 | |
| SCHEMBL22209406 | 0.83 | CCR1 (0.48) | ALDH1A1KCNK3ELANEPREPTAAR1 | |
| SCHEMBL18621662 | 0.83 | CCR1 (0.48) | ALDH1A1KCNK3ELANEPREPTAAR1 | |
| SCHEMBL22209497 | 0.82 | TAAR1 (0.49) | ALDH1A1ELANEPREPTAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |