SCHEMBL18619611

SCHEMBL18619611

Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)sc1C(=O)NCCNCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.35
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
ALPG P10696 1/20 0.30
ALOX12 P18054 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2501780 0.92 CCR1 (0.38) CCR1KDM4EALDH1A1LMNATP53
SCHEMBL20230401 0.89 CCR1 (0.37) CCR1
SCHEMBL2496669 0.88 CCR1 (0.35) CCR1LMNA
SCHEMBL2499572 0.87 CCR1 (0.35) CCR1
SCHEMBL21586659 0.86 CCR1 (0.34) CCR1
SCHEMBL19275537 0.85 CCR1 (0.34) CCR1
SCHEMBL20560059 0.84 CCR1 (0.31) CCR1
SCHEMBL2495760 0.84 CCR1 (0.36) CCR1
SCHEMBL25586455 0.84 CCR1 (0.39) CCR1
SCHEMBL20921637 0.82 KDM4E (0.32) KDM4EALDH1A1LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017040742-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-03-09 WO disclosed