Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25586455 | 0.95 | CCR1 (0.39) | CCR1 | |
| SCHEMBL2501780 | 0.94 | CCR1 (0.38) | CCR1LMNA | |
| Lotilaner SCHEMBL16860871 | 0.92 | CCR1 (0.33) | CCR1LMNA | |
| Lotilaner SCHEMBL2502148 | 0.92 | CCR1 (0.33) | CCR1LMNA | |
| SCHEMBL2495760 | 0.92 | CCR1 (0.36) | CCR1 | |
| SCHEMBL23874305 | 0.92 | CCR1 (0.33) | CCR1LMNA | |
| SCHEMBL2505425 | 0.92 | CCR1 (0.33) | CCR1LMNA | |
| SCHEMBL2499572 | 0.92 | CCR1 (0.35) | CCR1 | |
| SCHEMBL2507276 | 0.90 | CCR1 (0.35) | CCR1 | |
| SCHEMBL2507781 | 0.90 | CCR1 (0.35) | CCR1LMNAPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008329-B1 | ISOXAZOLINE COMPOUNDS FOR USE IN TREATING DEMODICOSIS | INTERVET INT BV (NL) | 2025-06-11 | — | — | EP | claimed |
| EP-2833866-B2 | SOFT CHEWABLE PHARMACEUTICAL PRODUCTS | INTERVET INT BV (NL) | 2024-11-27 | — | — | EP | claimed |
| EP-4430947-A1 | THERAPEUTIC USE OF ISOXAZOLINE COMPOUNDS, COMPOSITION OF ISOXAZOLINE COMPOUNDS AND KIT FOR THERAPEUTIC USE | Przedsiebiorstwo Wielobranzowe "Vet-Agro" Sp. Z O.O. (PL) | 2024-09-18 | — | — | EP | claimed |
| EP-2833867-B2 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INT BV (NL) | 2023-05-10 | — | — | EP | claimed |
| CN-108685894-B | Soft chewable pharmaceutical product | 英特维特国际股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| US-11285101-B2 | Soft chewable pharmaceutical products | INTERVET INC. (US) | 2022-03-29 | — | — | US | claimed |
| US-20190201332-A1 | Soft Chewable Pharmaceutical Products | INTERVET INC. (US) | 2019-07-04 | — | — | US | claimed |
| EP-3079474-B1 | ANTIPARASITIC USE OF ISOXAZOLINE COMPOUNDS | INTERVET INT BV (NL) | 2019-07-03 | — | — | EP | claimed |
| US-20190117565-A1 | Soft Chewable Pharmaceutical Product | INTERVET INC. (US) | 2019-04-25 | — | — | US | claimed |
| US-20190117564-A1 | Soft Chewable Pharmaceutical Products | INTERVET INC. (US) | 2019-04-25 | — | — | US | claimed |
| US-20170266165-A1 | Soft Chewable Pharmaceutical Products | INTERVET INC. (US) | 2017-09-21 | — | — | US | claimed |
| EP-2833867-B1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INT BV (NL) | 2017-05-17 | — | — | EP | claimed |
| US-20170100377-A1 | Solid Oral Pharmaceutical Compositions for Isoxazoline Compounds | INTERVET INC. (US) | 2017-04-13 | — | — | US | claimed |
| US-20150057239-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INC. | 2015-02-26 | — | — | US | claimed |
| US-20150057321-A1 | SOFT CHEWABLE PHARMACEUTICAL PRODUCTS | INTERVET INC. | 2015-02-26 | — | — | US | claimed |
| EP-2833867-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | Intervet International B.V. (NL) | 2015-02-11 | — | — | EP | claimed |
| EP-2833866-A1 | SOFT CHEWABLE PHARMACEUTICAL PRODUCTS | Intervet International B.V. (NL) | 2015-02-11 | — | — | EP | claimed |
| WO-2013150052-A1 | SOFT CHEWABLE PHARMACEUTICAL PRODUCTS | INTERVET INTERNATIONAL B.V. (NL) | 2013-10-10 | — | — | WO | claimed |
| WO-2013150055-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2013-10-10 | — | — | WO | claimed |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ELANCO TIERGESUNDHEIT AG (CH) | 2011-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170100377-A1 | Solid Oral Pharmaceutical Compositions for Isoxazoline Compounds | CYP3A7, SI, CYP2A7 | CCR1 3053/4885LMNA 3403/4885PIK3CA 1958/4885 |
| US-20150057321-A1 | SOFT CHEWABLE PHARMACEUTICAL PRODUCTS | PAM, TAS2R46, TAS2R16 | CCR1 3764/4885LMNA 1522/4885PIK3CA 3165/4885 |
| US-11285101-B2 | Soft chewable pharmaceutical products | PAM, TAS2R46, TAS2R16 | CCR1 3764/4885LMNA 1522/4885PIK3CA 3165/4885 |
| US-20150057239-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | CYP3A7, SI, CYP2A7 | CCR1 3053/4885LMNA 3403/4885PIK3CA 1958/4885 |
| US-20190117564-A1 | Soft Chewable Pharmaceutical Products | PAM, TAS2R46, TAS2R16 | CCR1 3764/4885LMNA 1522/4885PIK3CA 3165/4885 |
| US-20170266165-A1 | Soft Chewable Pharmaceutical Products | PAM, TAS2R46, TAS2R16 | CCR1 3764/4885LMNA 1522/4885PIK3CA 3165/4885 |
| US-20190117565-A1 | Soft Chewable Pharmaceutical Product | PAM, TAS2R46, TAS2R16 | CCR1 3686/4885LMNA 1521/4885PIK3CA 3161/4885 |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ACHE, VDAC1, VDAC2 | CCR1 4087/4885LMNA 3796/4885PIK3CA 2062/4885 |
| US-20190201332-A1 | Soft Chewable Pharmaceutical Products | PAM, TAS2R46, TAS2R16 | CCR1 3764/4885LMNA 1522/4885PIK3CA 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.