Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20484664 | 0.90 | LTA4H (0.49) | ELANESIGMAR1CCR1ACECMA1 | |
| SCHEMBL18619616 | 0.90 | LTA4H (0.49) | ELANESIGMAR1CCR1ACECMA1 | |
| SCHEMBL18621647 | 0.88 | CCR1 (0.53) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL22209463 | 0.88 | CCR1 (0.53) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL22209461 | 0.85 | CCR1 (0.52) | ELANEALDH1A1CCR1ACE | |
| SCHEMBL22209497 | 0.83 | TAAR1 (0.49) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL18621642 | 0.83 | TAAR1 (0.49) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL22209400 | 0.81 | CCR1 (0.55) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL18619643 | 0.81 | CCR1 (0.55) | ELANEALDH1A1CCR1ACECMA1 | |
| SCHEMBL9814462 | 0.79 | ACE (0.49) | ELANECCR1ACECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |