Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 5/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18619652 | 0.88 | PREP (0.53) | PREPLMNAELANECTSGFAP | |
| SCHEMBL18619650 | 0.84 | PREP (0.55) | PREPELANECTSG | |
| SCHEMBL20485166 | 0.84 | PREP (0.55) | PREPELANECTSG | |
| SCHEMBL18621027 | 0.83 | PREP (0.53) | PREPLMNAELANECTSGTAAR1 | |
| SCHEMBL22209481 | 0.83 | PREP (0.53) | PREPLMNAELANECTSGTAAR1 | |
| SCHEMBL18619576 | 0.77 | PREP (0.42) | PREPELANECTSGCCR1DPP8 | |
| SCHEMBL13951053 | 0.75 | ELANE (0.51) | PREPELANECTSGTAAR1 | |
| SCHEMBL13928253 | 0.75 | ELANE (0.51) | PREPELANECTSGTAAR1 | |
| SCHEMBL22798449 | 0.75 | ELANE (0.55) | PREPELANECTSG | |
| SCHEMBL18586542 | 0.75 | ELANE (0.55) | PREPELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |