Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 12/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209481 | 1.00 | PREP (0.53) | PREPELANECTSGTAAR1ACE | |
| SCHEMBL22209405 | 0.91 | ELANE (0.53) | PREPELANECTSGTAAR1 | |
| SCHEMBL18621665 | 0.91 | ELANE (0.53) | PREPELANECTSGTAAR1 | |
| SCHEMBL20485166 | 0.89 | PREP (0.55) | PREPELANECTSGACE | |
| SCHEMBL18619650 | 0.89 | PREP (0.55) | PREPELANECTSGACE | |
| SCHEMBL22209505 | 0.88 | CCR1 (0.54) | PREPELANETAAR1 | |
| SCHEMBL22209486 | 0.88 | PREP (0.52) | PREPELANECTSGTAAR1ACE | |
| SCHEMBL22209430 | 0.88 | LMNA (0.53) | PREPELANECTSGTAAR1ACE | |
| SCHEMBL18619671 | 0.88 | LMNA (0.53) | PREPELANECTSGTAAR1ACE | |
| SCHEMBL22209498 | 0.88 | PREP (0.52) | PREPELANECTSGTAAR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |