Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1862010

CN1CC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CN(C)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 13/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1860359 0.95 CSF1R (0.74) CSF1R
Trifluoroacetic Acid SCHEMBL1863165 0.92 CSF1R (0.69) CSF1R
Trifluoroacetic Acid SCHEMBL1859712 0.88 CSF1R (0.67) CSF1R
Trifluoroacetic Acid SCHEMBL1856490 0.87 CSF1R (0.67) CSF1R
SCHEMBL12422245 0.86 CSF1R (0.76) CSF1R
SCHEMBL1858586 0.86 CSF1R (0.61) CSF1R
SCHEMBL1855020 0.86 CSF1R (0.61) CSF1R
SCHEMBL12408036 0.85 CSF1R (0.63) CSF1R
SCHEMBL1864639 0.85 CSF1R (0.74) CSF1R
SCHEMBL14384614 0.83 CSF1R (0.57) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110195960-A1 INHIBITORS OF C-FMS KINASE ILLIG CARL R 2011-08-11 US disclosed
EP-2021335-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2011-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195960-A1 INHIBITORS OF C-FMS KINASE MUSK, FRK, FES CSF1R 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.