Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | BCR | P11274 | 3/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18621855 | 0.91 | MEN1 (0.34) | MEN1ESR1KMT2AABL1ABCB1 | |
| SCHEMBL20382348 | 0.85 | HRH3 (0.31) | ESR1 | |
| SCHEMBL18308717 | 0.83 | MEN1 (0.41) | MEN1ESR1KMT2AABL1ABCB1 | |
| SCHEMBL18308720 | 0.79 | MEN1 (0.48) | MEN1ESR1KMT2AABL1ABCB1 | |
| SCHEMBL20382345 | 0.77 | HRH3 (0.38) | ESR1CHKATAAR1 | |
| SCHEMBL26031807 | 0.75 | TAAR1 (0.54) | MEN1ESR1KMT2ATAAR1AGXT | |
| SCHEMBL18621838 | 0.75 | RXRA (0.39) | MEN1ESR1KMT2AABL1ABCB1 | |
| SCHEMBL18308715 | 0.74 | PTPN5 (0.42) | MEN1ESR1KMT2ATAAR1MAOB | |
| SCHEMBL25953997 | 0.74 | — | — | |
| SCHEMBL12635517 | 0.73 | AGXT (0.41) | MEN1ESR1KMT2AABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594283-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |