SCHEMBL18622286

SCHEMBL18622286

Cc1nc2occn2c1C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 2/20 0.30
ATP4B P51164 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5047019 0.67
SCHEMBL14006980 0.65 PRKD3 (0.32)
SCHEMBL14752116 0.65 NR1I3 (0.30)
SCHEMBL5044179 0.63
SCHEMBL5040063 0.61
SCHEMBL31452710 0.58
SCHEMBL14341719 0.58
SCHEMBL9609556 0.57 PRKD3 (0.30)
SCHEMBL23107422 0.57 ATP4A (0.41) ATP4AATP4B
SCHEMBL16920990 0.56 CYP1A2 (0.41) ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593109-B2 Bicyclic agonists of GPR131 and uses thereof CYMABAY THERAPEUTICS, INC. (US) 2017-03-14 US disclosed