SCHEMBL18622810

SCHEMBL18622810

CC1(C)c2cc(-c3ccc4c(c3)Oc3cc5ccccc5cc3O4)ccc2-c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ EDNRA P25101 5/20 0.35
▸ PTGER4 P35408 1/20 0.33
▸ EDNRB P24530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12306590 0.87 KDM4E (0.43) KDM4EATML3MBTL1PTGER4
SCHEMBL13443593 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1EDNRAPTGER4
SCHEMBL18622807 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1EDNRAPTGER4
SCHEMBL18622803 0.87 L3MBTL1 (0.47) KDM4EATML3MBTL1EDNRAPTGER4
SCHEMBL13444136 0.87 L3MBTL1 (0.50) KDM4EATML3MBTL1PTGER4
SCHEMBL12306534 0.87 L3MBTL1 (0.50) KDM4EATML3MBTL1PTGER4
SCHEMBL13443606 0.87 L3MBTL1 (0.50) KDM4EATML3MBTL1PTGER4
SCHEMBL13557595 0.85 L3MBTL1 (0.46) KDM4EATML3MBTL1EDNRAPTGER4
SCHEMBL13444300 0.85 L3MBTL1 (0.49) KDM4EATML3MBTL1PTGER4
SCHEMBL13444405 0.85 L3MBTL1 (0.49) KDM4EATML3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same OCIAD1, OXA1L, OCIAD2 KDM4E 3223/4885ATM 3873/4885L3MBTL1 50/4885
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OXA1L, CYP1A1 KDM4E 3224/4885ATM 3712/4885L3MBTL1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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