Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910847 | 0.79 | TSHR (0.54) | TSHRSMN1; SMN2 | |
| SCHEMBL11972934 | 0.75 | TSHR (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL29253927 | 0.75 | TSHR (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL28282921 | 0.72 | — | — | |
| SCHEMBL28281612 | 0.69 | TSHR (0.46) | TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28452466 | 0.68 | — | — | |
| SCHEMBL8060557 | 0.67 | TSHR (0.35) | TSHR | |
| SCHEMBL12424293 | 0.66 | ALDH1A1 (0.39) | FOLH1TSHR | |
| SCHEMBL12871390 | 0.66 | — | — | |
| SCHEMBL31521503 | 0.66 | TSHR (0.43) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593069-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |