Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 4/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16932504 | 1.00 | PIP4K2A (0.32) | PIP4K2ANNMTPRMT5WDR77P2RY1 | |
| SCHEMBL16932515 | 0.89 | PRMT5 (0.34) | PIP4K2ANNMTPRMT5WDR77 | |
| SCHEMBL18626339 | 0.89 | PRMT5 (0.34) | PIP4K2ANNMTPRMT5WDR77 | |
| SCHEMBL16932517 | 0.89 | PRMT5 (0.34) | PIP4K2ANNMTPRMT5WDR77 | |
| SCHEMBL16932511 | 0.85 | DUT (0.30) | — | |
| SCHEMBL16932522 | 0.84 | — | — | |
| SCHEMBL10004893 | 0.83 | PRMT5 (0.37) | PIP4K2APRMT5WDR77P2RY1ACACB | |
| SCHEMBL192272 | 0.83 | PRMT5 (0.37) | PIP4K2APRMT5WDR77P2RY1ACACB | |
| SCHEMBL10004894 | 0.83 | PRMT5 (0.37) | PIP4K2APRMT5WDR77P2RY1ACACB | |
| SCHEMBL192508 | 0.78 | NAE1 (0.58) | UBA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593121-B2 | Indole substituted pyrrolopyrimidinyl inhibitors of Uba6 | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-03-14 | — | — | US | disclosed |