Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626739 | 0.91 | PRMT6 (0.44) | GAAPOLBPRMT6THRBKDM4E | |
| SCHEMBL18067910 | 0.82 | HPGD (0.44) | CELGAAPOLBCYP1A2DAO | |
| SCHEMBL23665620 | 0.73 | PRMT6 (0.58) | GAAPRMT6THRBDAOKDM4E | |
| SCHEMBL18067903 | 0.72 | CYP1A2 (0.46) | CELGAAPOLBCYP1A2HPGD | |
| SCHEMBL18067912 | 0.72 | HPGD (0.37) | CELGAAPRMT6DAOKDM4E | |
| SCHEMBL15215068 | 0.71 | IDO1 (0.37) | CELGAAPOLBCYP1A2MEN1 | |
| SCHEMBL13209028 | 0.70 | KDM4C (0.47) | POLBPRMT6MEN1ALDH1A1KMT2A | |
| SCHEMBL3360573 | 0.70 | PRMT6 (0.52) | GAAPOLBPRMT6THRBKDM4E | |
| SCHEMBL29064511 | 0.69 | HPGD (0.56) | CELPOLBMEN1ALDH1A1HPGD | |
| SCHEMBL16191644 | 0.68 | MAOB (0.55) | CELGAAPOLBCYP1A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |