Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14745586 | 0.94 | TSHR (0.31) | EDNRBTSHRAADATP2RX3MEN1 | |
| SCHEMBL14745587 | 0.94 | TSHR (0.31) | EDNRBTSHRAADATP2RX3MEN1 | |
| SCHEMBL18628153 | 0.89 | EDNRB (0.36) | EDNRBTSHRAADATMEN1ALDH1A1 | |
| SCHEMBL16428920 | 0.86 | TSHR (0.35) | EDNRBTSHRAADATMEN1ALDH1A1 | |
| SCHEMBL16428921 | 0.86 | TSHR (0.35) | EDNRBTSHRAADATMEN1ALDH1A1 | |
| SCHEMBL14745686 | 0.80 | EDNRB (0.35) | EDNRBTSHRAADATP2RX3MEN1 | |
| SCHEMBL14746260 | 0.80 | EDNRB (0.36) | EDNRBTSHRAADATP2RX3MEN1 | |
| SCHEMBL14745732 | 0.79 | — | — | |
| SCHEMBL14745730 | 0.79 | — | — | |
| SCHEMBL18628123 | 0.78 | EDNRB (0.38) | EDNRBTSHRAADATALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750678-B1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS INC (US) | 2017-03-22 | — | — | EP | disclosed |