Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428920 | 0.95 | TSHR (0.35) | EDNRBTSHRAADATPTGDR2ALDH1A1 | |
| SCHEMBL16428921 | 0.95 | TSHR (0.35) | EDNRBTSHRAADATPTGDR2ALDH1A1 | |
| SCHEMBL18628149 | 0.89 | EDNRB (0.35) | EDNRBTSHRAADATALDH1A1MEN1 | |
| SCHEMBL18628123 | 0.88 | EDNRB (0.38) | EDNRBTSHRAADATPTGDR2SRD5A1 | |
| SCHEMBL14745586 | 0.85 | TSHR (0.31) | EDNRBTSHRAADATALDH1A1MEN1 | |
| SCHEMBL14745587 | 0.85 | TSHR (0.31) | EDNRBTSHRAADATALDH1A1MEN1 | |
| SCHEMBL14746131 | 0.84 | TSHR (0.35) | EDNRBTSHRAADATPTGDR2ALDH1A1 | |
| SCHEMBL18628127 | 0.74 | EDNRB (0.38) | EDNRBTSHRAADATSRD5A1SRD5A2 | |
| SCHEMBL14745686 | 0.71 | EDNRB (0.35) | EDNRBTSHRAADATALDH1A1KDM4E | |
| SCHEMBL14745732 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750678-B1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS INC (US) | 2017-03-22 | — | — | EP | disclosed |