Pyridine

Pyridine

SCHEMBL18628593

Nc1nc(N)nc(N)n1.c1ccncc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ADORA2A P29274 7/20 0.46
ADORA1 P30542 5/20 0.46
POLB P06746 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ADORA2B P29275 1/20 0.46
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSP90AA1 P07900 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CHRM1 P11229 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27645773 0.84 TSHR (0.45) TSHRNAPRTTDP1ADORA2AADORA1
Benzene SCHEMBL19253562 0.83 ADORA2A (0.58) ADORA2AADORA1POLBADORA3ADORA2B
Pyridine SCHEMBL28037279 0.79 HSP90AA1 (0.71) TSHRNAPRTTDP1ADORA2AADORA1
Pyridine SCHEMBL2120301 0.75
Benzene SCHEMBL10751789 0.75 TSHR (1.00) TSHRNAPRTTDP1ALDH1A1MEN1
Pyridine SCHEMBL933604 0.75 TSHR (1.00) TSHRNAPRTTDP1ALDH1A1MEN1
Pyridine SCHEMBL9037865 0.75 TSHR (1.00) TSHRNAPRTTDP1ALDH1A1MEN1
Pyridine SCHEMBL16 0.75
SCHEMBL3052767 0.75 TSHR (1.00) TSHRNAPRTTDP1ALDH1A1MEN1
Benzene SCHEMBL1261317 0.75 TSHR (1.00) TSHRNAPRTTDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10427982-B2 Method of carbon coating on nanoparticle and carbon coated nanoparticle produced by the same KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2019-10-01 US disclosed
US-20170081248-A1 METHOD OF CARBON COATING ON NANOPARTICLE AND CARBON COATED NANOPARTICLE PRODUCED BY THE SAME KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2017-03-23 US disclosed
EP-3144277-A1 METHOD OF CARBON COATING ON NANOPARTICLE AND CARBON COATED NANOPARTICLE PRODUCED BY THE SAME Korea Institute of Energy Research (KR) 2017-03-22 EP disclosed