Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490150 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL16 | 1.00 | — | — | |
| SCHEMBL34466311 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL9037865 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL180431 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL1654468 | 1.00 | — | — | |
| SCHEMBL3052767 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Benzene SCHEMBL10751789 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Benzene SCHEMBL1261317 | 1.00 | TSHR (1.00) | TSHRNAPRTTDP1NOTUMSLC6A2 | |
| Pyridine SCHEMBL30107114 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013042120-A2 | SYNTHETIC UBIQUITINS AND USE THEREOF IN DRUG SCREENING ASSAYS | PROTEOLOGICS LTD (IL) | 2013-03-28 | — | — | WO | claimed |
| EP-4271827-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | Abbott Diabetes Care, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022147496-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | ABBOTT DIABETES CARE INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| US-20220202326-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | ABBOTT DIABETES CARE INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-20210333269-A1 | Kits for Using Bispyridines to Improve Labeling of Nucleophiles | AGILENT TECHNOLOGIES, INC. (US) | 2021-10-28 | — | — | US | disclosed |
| US-11092595-B2 | Use of bispyridines to improve labeling of nucleophiles | AGILENT TECHNOLOGIES, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| CN-110649245-A | Active carbon loaded nano-scale N-doped cobalt phthalocyanine composite material and in-situ solid phase preparation method and application thereof | 陕西科技大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-109482235-A | A kind of preparation method and applications of the metal nano catalyst of the doped meso-porous carbon load of N- | 合肥工业大学 | 2019-03-19 | — | — | CN | disclosed |
| US-20190041384-A1 | USE OF BISPYRIDINES TO IMPROVE LABELING OF NUCLEOPHILES | PROZYME, INC. | 2019-02-07 | — | — | US | disclosed |
| EP-3419963-A1 | USE OF BISPYRIDINES TO IMPROVE LABELING OF NUCLEOPHILES | Prozyme, Inc. (US) | 2019-01-02 | — | — | EP | disclosed |
| WO-1988008839-A1 | PROCESS FOR THE PRODUCTION OF 2,3,5,6-TETRACHLOROPYRIDINE AND 2,3,6-TRICHLOROPYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1988-11-17 | — | — | WO | disclosed |
| US-4785112-A | CHLORINATION OF 2,6-DICHLOROPYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4404394-A | FJROM BUTADIENE, CARBON MONOXIDE AND AN ALCOHOL, COBALT CARBONYL CATALYSIS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-09-13 | — | — | US | disclosed |
| US-4332966-A | N-HETEROCYCLE SOLVENT FOR REACTION OF BUTADIENE, CARBON MONOXIDE AND AH ALCOHOL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4267335-A | Substituted 2,2'-bipyridyl compounds and process for preparing same | REILLY TAR & CHEMICAL CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4263439-A | FROM AMMONIA, ACETALDEHYDE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4239892-A | FROM ACETALDEHYDE AND AMMONIA USING A SILICA-ALUMINA CATALYST CONTAINING AN ION EXCHANGED METAL ION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-12-16 | — | — | US | disclosed |
| US-4179576-A | FROM ACETALDEHYDE AND AMMONIA IN GAS PHASE USING ION EXCHANGED ALUMINA-SILICA CATALYST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-12-18 | — | — | US | disclosed |
| US-4177349-A | BY-PRODUCT INHIBITION | REILLY TAR & CHEMICAL CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |
| US-4054499-A | PHOTOLYTIC CHLORINATION OF PYRIDINE | SEITETSU KAGAKU CO., LTD. (JA) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190041384-A1 | USE OF BISPYRIDINES TO IMPROVE LABELING OF NUCLEOPHILES | PTMS, BTD, DPYD | TSHR 2601/4885NAPRT 256/4885TDP1 641/4885 |
| US-11092595-B2 | Use of bispyridines to improve labeling of nucleophiles | PTMS, BTD, DPYD | TSHR 2601/4885NAPRT 256/4885TDP1 641/4885 |
| US-20210333269-A1 | Kits for Using Bispyridines to Improve Labeling of Nucleophiles | DPYD, UNG, BTD | TSHR 2524/4885NAPRT 259/4885TDP1 519/4885 |
| US-20220202326-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | GPX4, LPO, PRDX3 | TSHR 1812/4885NAPRT 1492/4885TDP1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.