SCHEMBL18628630

SCHEMBL18628630

CCOC(=O)OCC(F)F.O=C(O)OCCOC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
SOAT1 P35610 1/20 0.40
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
CYP2D6 P10635 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18628625 0.92 ALDH1A1 (0.41) ALDH1A1SOAT1MGAMGAASI
Bicarbonate SCHEMBL14972904 0.88 ALDH1A1 (0.56) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL575131 0.88 ALDH1A1 (0.62) ALDH1A1SOAT1LMNAHSD17B10TSHR
SCHEMBL30747201 0.88 ALDH1A1 (0.62) ALDH1A1SOAT1LMNAHSD17B10TSHR
Bicarbonate SCHEMBL20656642 0.85 ALDH1A1 (0.33) ALDH1A1SOAT1CYP2D6SMN1; SMN2
SCHEMBL138615 0.84 ALDH1A1 (0.68) ALDH1A1SOAT1LMNAHSD17B10TSHR
SCHEMBL14781523 0.82 ALDH1A1 (0.65) ALDH1A1SOAT1LMNAHSD17B10TSHR
SCHEMBL2700374 0.81 ALDH1A1 (0.43) ALDH1A1SOAT1
SCHEMBL5532875 0.80 ALDH1A1 (0.56) ALDH1A1SOAT1LMNAHSD17B10TSHR
SCHEMBL6365093 0.80 ALDH1A1 (0.56) ALDH1A1SOAT1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2450997-B1 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEM CORP (JP) 2017-03-22 EP disclosed