Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629001 | 0.86 | PDK1 (0.38) | IDO1 | |
| SCHEMBL24059747 | 0.83 | IDO1 (0.30) | IDO1 | |
| SCHEMBL18629117 | 0.77 | NRAS (0.42) | — | |
| SCHEMBL10304064 | 0.76 | PTPN11 (0.42) | — | |
| SCHEMBL24059784 | 0.76 | — | — | |
| SCHEMBL16152886 | 0.75 | MAPK14 (0.34) | — | |
| SCHEMBL10304292 | 0.74 | PDK1 (0.39) | ATR | |
| SCHEMBL24059785 | 0.73 | — | — | |
| SCHEMBL18051934 | 0.73 | KMT2A (0.34) | — | |
| SCHEMBL8943059 | 0.73 | JAK2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |