SCHEMBL18632012

SCHEMBL18632012

CCP(=O)(O)Oc1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
BLM P54132 1/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 1/20 0.41
CETP P11597 1/20 0.39
FDPS P14324 1/20 0.38
CXCL12 P48061 1/20 0.38
MAOB P27338 1/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
SRC P12931 1/20 0.36
CYP2D6 P10635 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9583670 0.80 SRC (0.59) CYP2C19BLMCYP2C9CETPSRC
SCHEMBL4133273 0.80 HPGD (0.46) CYP2C19SMN1; SMN2BLMHPGDMAPK1
SCHEMBL17626580 0.78 SRC (0.57) CYP2C19CYP2C9CETPSRCTDP1
SCHEMBL17626503 0.78 SRC (0.57) CYP2C19CYP2C9CETPSRCTDP1
SCHEMBL17626531 0.78 SRC (0.57) CYP2C19CYP2C9CETPSRCTDP1
SCHEMBL28074473 0.78 CYP2C19 (0.58) CYP2C19SMN1; SMN2BLMHPGDMAPK1
SCHEMBL17169180 0.77 CES2 (0.53) CYP2C19SMN1; SMN2BLMHPGDMAPK1
SCHEMBL6473557 0.77 SRC (0.60) CYP2C19BLMHPGDCYP1A2CYP2C9
SCHEMBL4946779 0.75 HPGD (0.49) CYP2C19SMN1; SMN2BLMHPGDMAPK1
Fluoride SCHEMBL31047201 0.75 CES2 (0.52) CYP2C19SMN1; SMN2BLMHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
US-10290901-B2 2019-05-14 US disclosed
US-20170084955-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-23 US disclosed