Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 17/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | INSR | P06213 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.57 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417760 | 0.88 | EGFR (0.66) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL255884 | 0.87 | FBP1 (0.58) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL1418424 | 0.87 | EGFR (0.66) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL18633000 | 0.86 | EGFR (0.59) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL1190546 | 0.86 | EGFR (0.68) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL18633122 | 0.86 | FBP1 (0.54) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL1418776 | 0.86 | KDR (0.66) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL18632990 | 0.83 | EGFR (0.56) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL1191334 | 0.83 | EGFR (0.70) | FBP1EGFRKDREPHB4ERBB2 | |
| SCHEMBL1191324 | 0.83 | EGFR (0.70) | FBP1EGFRKDREPHB4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |