Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838833 | 0.84 | APP (0.56) | MAOBAPP | |
| SCHEMBL757316 | 0.82 | MAOB (0.53) | MAOBAPPCYP4F2CYP4A11NR4A2 | |
| SCHEMBL228033 | 0.82 | P4HTM (0.58) | MAOBNR4A2 | |
| SCHEMBL27550091 | 0.79 | MAOB (0.80) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL16761844 | 0.79 | MAOA (0.52) | MAOBMEN1KMT2A | |
| SCHEMBL29468690 | 0.79 | CYP4F2 (0.42) | MAOBCYP4F2CYP4A11 | |
| SCHEMBL751951 | 0.78 | MEN1 (0.44) | MEN1KMT2AGRM5 | |
| SCHEMBL19604518 | 0.78 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL11959895 | 0.78 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL15776007 | 0.78 | CYP4F2 (0.60) | CYP4F2CYP4A11CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |