Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | BACE1 | P56817 | 6/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18633617 | 0.84 | CCR1 (0.41) | CCR1CHRM2CCR5 | |
| SCHEMBL18895961 | 0.84 | CCR1 (0.41) | CCR1CHRM2CCR5 | |
| SCHEMBL10287996 | 0.83 | CCR1 (0.49) | CCR1CHRM2CCR5 | |
| SCHEMBL18896016 | 0.83 | CCR1 (0.40) | CCR1CHRM2CCR5 | |
| SCHEMBL18633615 | 0.83 | CCR1 (0.39) | CCR1CHRM2CCR5 | |
| SCHEMBL18895968 | 0.82 | CCR1 (0.40) | CCR1CHRM2CCR5KCNH2 | |
| SCHEMBL15478324 | 0.82 | CCR1 (0.39) | CCR1CHRM2CCR5 | |
| SCHEMBL15478321 | 0.82 | CCR1 (0.43) | CCR1MEN1KMT2ATP53 | |
| SCHEMBL15478317 | 0.82 | CCR1 (0.65) | CCR1BCHEACHEBACE1CCR2 | |
| SCHEMBL3838031 | 0.82 | CCR1 (0.65) | CCR1BCHEACHEBACE1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |