Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18633617 | 0.90 | CCR1 (0.41) | CCR1CHRM2CCR5MCHR1 | |
| SCHEMBL15478324 | 0.88 | CCR1 (0.39) | CCR1CHRM2CCR5 | |
| SCHEMBL18896016 | 0.87 | CCR1 (0.40) | CCR1CHRM2CCR5 | |
| SCHEMBL18895968 | 0.86 | CCR1 (0.40) | CCR1CHRM2CCR5MCHR1 | |
| SCHEMBL18633615 | 0.85 | CCR1 (0.39) | CCR1CHRM2CCR5 | |
| SCHEMBL18896015 | 0.85 | CCR1 (0.38) | CCR1CHRM2CCR5 | |
| SCHEMBL18633616 | 0.85 | CCR1 (0.36) | CCR1CHRM2CCR5MCHR1 | |
| SCHEMBL18633821 | 0.84 | CCR1 (0.43) | CCR1CHRM2CCR5 | |
| SCHEMBL16312654 | 0.83 | CCR1 (0.60) | CCR1CHRM2CCR5MCHR1 | |
| SCHEMBL15478321 | 0.79 | CCR1 (0.43) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |