Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577123 | 0.83 | SSTR4 (0.47) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL4662657 | 0.83 | HDAC3 (0.46) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL407573 | 0.83 | ABCB1 (0.44) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL2260872 | 0.83 | HDAC3 (0.43) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL2722481 | 0.82 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2CTSL | |
| SCHEMBL25391164 | 0.82 | NSD2 (0.45) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL2586342 | 0.82 | SLC6A2 (0.44) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL30954944 | 0.82 | TSHR (0.45) | SNCAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1852981 | 0.81 | HDAC3 (0.45) | SNCANSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL14125767 | 0.81 | CTSS (0.45) | SNCANSD2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2713722-B1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | RECEPTOS LLC (US) | 2017-03-15 | — | — | EP | disclosed |