Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870981 | 0.93 | BCL2 (0.74) | BCL2 | |
| SCHEMBL27075547 | 0.92 | BCL2 (0.83) | BCL2 | |
| SCHEMBL1699879 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30314006 | 0.91 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1861888 | 0.90 | BCL2 (0.81) | BCL2 | |
| SCHEMBL19292332 | 0.88 | BCL2 (0.83) | BCL2 | |
| SCHEMBL21573216 | 0.87 | BCL2 (0.73) | BCL2 | |
| SCHEMBL1871704 | 0.86 | BCL2 (0.83) | BCL2 | |
| SCHEMBL1869537 | 0.86 | BCL2 (0.76) | BCL2 | |
| SCHEMBL1867507 | 0.85 | BCL2 (0.87) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |