Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634584 | 0.74 | PDE10A (0.45) | PDE10A | |
| SCHEMBL21101406 | 0.66 | PDE10A (0.53) | PDE10A | |
| SCHEMBL10277559 | 0.65 | PDE10A (0.52) | PDE10A | |
| SCHEMBL10309446 | 0.60 | PDE10A (1.00) | PDE10A | |
| SCHEMBL10309445 | 0.59 | PDE10A (0.57) | PDE10A | |
| SCHEMBL10345238 | 0.58 | PDE10A (0.72) | PDE10A | |
| SCHEMBL28454970 | 0.58 | PDE10A (0.43) | PDE10A | |
| SCHEMBL18634482 | 0.57 | PDE10A (0.46) | PDE10A | |
| SCHEMBL27940721 | 0.56 | PDE10A (0.41) | PDE10A | |
| SCHEMBL10277451 | 0.55 | PDE10A (0.41) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663565-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | disclosed |