Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 9/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.62 |
| ▸ | PRKCA | P17252 | 7/20 | 0.54 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.53 |
| ▸ | PRKCG | P05129 | 2/20 | 0.53 |
| ▸ | PRKCB | P05771 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PRKACG | P22612 | 2/20 | 0.53 |
| ▸ | PRKACB | P22694 | 2/20 | 0.53 |
| ▸ | PRKCH | P24723 | 2/20 | 0.53 |
| ▸ | PRKCI | P41743 | 2/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19050455 | 1.00 | PRKCQ (0.66) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570607 | 0.88 | PRKCQ (0.84) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570605 | 0.88 | PRKCQ (0.84) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570348 | 0.88 | PRKCQ (0.84) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570349 | 0.85 | PRKCQ (0.85) | PRKCQROCK2PRKCAMAP3K5NTRK1 | |
| SCHEMBL12570608 | 0.85 | PRKCQ (0.85) | PRKCQROCK2PRKCAMAP3K5NTRK1 | |
| SCHEMBL12570606 | 0.85 | PRKCQ (0.85) | PRKCQROCK2PRKCAMAP3K5NTRK1 | |
| SCHEMBL18635718 | 0.83 | PRKCQ (0.79) | PRKCQROCK2PRKCAMAP3K5NTRK1 | |
| SCHEMBL30885079 | 0.77 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5NTRK1 | |
| SCHEMBL22197322 | 0.76 | PRKCQ (0.70) | PRKCQROCK2PRKCAMAP3K5PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277885-B1 | GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF | UNIV OVIEDO (ES) | 2017-03-15 | — | — | EP | disclosed |