SCHEMBL12570348

SCHEMBL12570348

C[C@H]1O[C@@H](n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)C(=O)NC4=O)C[C@@H](O)[C@@H]1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCQ Q04759 10/20 0.84
▸ ROCK2 O75116 9/20 0.79
▸ PRKCA P17252 7/20 0.59
▸ MAP3K5 Q99683 2/20 0.56
▸ CDK4 P11802 3/20 0.55
▸ CCND1 P24385 2/20 0.55
▸ PIM1 P11309 1/20 0.53
▸ FLT3 P36888 1/20 0.53
▸ PIM3 Q86V86 1/20 0.53
▸ PIM2 Q9P1W9 1/20 0.53
▸ PRKD3 O94806 3/20 0.52
▸ PRKCG P05129 3/20 0.52
▸ PRKCB P05771 3/20 0.52
▸ PRKCH P24723 3/20 0.52
▸ PRKCI P41743 3/20 0.52
▸ PRKCE Q02156 3/20 0.52
▸ PRKCZ Q05513 3/20 0.52
▸ PRKCD Q05655 3/20 0.52
▸ PRKD1 Q15139 3/20 0.52
▸ CDK2 P24941 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12570605 1.00 PRKCQ (0.84) PRKCQROCK2PRKCAMAP3K5CDK4
SCHEMBL12570607 1.00 PRKCQ (0.84) PRKCQROCK2PRKCAMAP3K5CDK4
SCHEMBL12570606 0.88 PRKCQ (0.85) PRKCQROCK2PRKCAMAP3K5
SCHEMBL12570349 0.88 PRKCQ (0.85) PRKCQROCK2PRKCAMAP3K5
SCHEMBL19050455 0.88 PRKCQ (0.66) PRKCQROCK2PRKCAMAP3K5CDK4
SCHEMBL18635358 0.88 PRKCQ (0.66) PRKCQROCK2PRKCAMAP3K5CDK4
SCHEMBL18635718 0.88 PRKCQ (0.79) PRKCQROCK2PRKCAMAP3K5
SCHEMBL12570608 0.88 PRKCQ (0.85) PRKCQROCK2PRKCAMAP3K5
SCHEMBL22197322 0.87 PRKCQ (0.70) PRKCQROCK2PRKCAMAP3K5CDK4
SCHEMBL18635724 0.87 PRKCQ (0.69) PRKCQROCK2PRKCAMAP3K5CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3184537-B1 GLYCOSYLATED INDOLOCARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIV OVIEDO (ES) 2020-07-08 — — EP disclosed
EP-3184537-A1 GLYCOSYLATED INDOLOCARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF Universidad De Oviedo (ES) 2017-06-28 — — EP disclosed
EP-2277885-B1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIV OVIEDO (ES) 2017-03-15 — — EP disclosed
US-20110136753-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIVERSIDAD DE OVIEDO (ES) 2011-06-09 — — US disclosed
EP-2277885-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF Universidad De Oviedo (ES) 2011-01-26 — — EP disclosed
WO-2009125042-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIVERSIDAD DE OVIEDO (ES) 2009-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136753-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF PYGB, INMT, SI PRKCQ 2262/4885ROCK2 315/4885PRKCA 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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