Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 14/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 14/20 | 0.45 |
| ▸ | BIRC3 | Q13489 | 12/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635985 | 0.95 | XIAP (0.45) | XIAPBIRC2BIRC3CFTR | |
| SCHEMBL18635814 | 0.85 | XIAP (0.52) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635962 | 0.81 | XIAP (0.41) | XIAPBIRC2BIRC3LPAR1LPAR5 | |
| SCHEMBL18635996 | 0.81 | XIAP (0.48) | XIAPBIRC2BIRC3 | |
| SCHEMBL17024633 | 0.79 | XIAP (0.57) | XIAPBIRC2BIRC3 | |
| SCHEMBL17024631 | 0.79 | XIAP (0.57) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635823 | 0.78 | CFTR (0.42) | XIAPBIRC2BIRC3TAS2R14LPAR1 | |
| SCHEMBL17024576 | 0.77 | XIAP (0.54) | XIAPBIRC2BIRC3 | |
| SCHEMBL17024578 | 0.77 | XIAP (0.54) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635934 | 0.77 | XIAP (0.41) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |