Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 17/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 16/20 | 0.41 |
| ▸ | BIRC3 | Q13489 | 14/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635934 | 0.94 | XIAP (0.41) | XIAPBIRC2BIRC3TDP1TACR1 | |
| SCHEMBL18635839 | 0.81 | XIAP (0.45) | XIAPBIRC2BIRC3LPAR1LPAR5 | |
| SCHEMBL18635963 | 0.79 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL17024508 | 0.79 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL17024510 | 0.79 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635814 | 0.78 | XIAP (0.52) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635985 | 0.76 | XIAP (0.45) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635996 | 0.75 | XIAP (0.48) | XIAPBIRC2BIRC3TACR1 | |
| SCHEMBL17024532 | 0.73 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL18635933 | 0.73 | XIAP (0.49) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |